enrichment of probiotic yogurt with broccoli sprout extract and its effect on helicobacter pylori

background and objective: antibiotic consumption is the main way to cure infection induced by helicobacter pylori. on the other hand, antibiotics have side effects on human body. so, finding an efficient way to replace antibiotic consumption seems necessary. the aim of this study was to investigate the effect of broccoli sprout extract on the viability of probiotic bacteria and yogurt’s physicochemical properties, and examine the synergistic effect of this extract with probiotics on helicobacter pylori growth inhibition. material and methods: four levels of broccoli sprout extract (22.5, 45, 90 and 180 mg ml-1) were prepared and their effect on probiotic yogurt samples was examined. moreover, their anti- helicobacter pylori effect was determined. results and conclusion: the research results revealed that broccoli sprout extract did not have any inhibitory effect on bifidobacterium lactis and lactobacillus acidophilus. the variations in acidity of the samples were not significant during storage. a positive correlation was observed between broccoli sprout extract concentration and syneresis. the findings showed the synergistic effect of broccoli sprout extract and probiotics on helicobacter pylori growth inhibition. therefore, using broccoli sprout extract and probiotic bacteria, we can produce a yogurt that is effective on the growth inhibition of helicobacter pylori. conflict of interest: the authors declare that there is no conflict of interest.